PliaFX® Advanced Fiber DBMs

PliaFX a is family of demineralized bone matrices (DBMs) contains optimally demineralized fibers1-3† with surface characteristics that set the standard for osseointegration.4-6†

The interlocking fiber microhooks in PliaFX grafts provide optimized handling characteristics.4,5,7,8† The fibers interlock to provide a moldable, intact graft that easily transfers to the surgical site, conforms to the surgical site, and resists migration.

References
1.Zhang Q, Jing D, Zhang Y, Miron RJ. Int J Oral Maxillofac Implants. 2018 May/June; 33(3):645–652. PMID: 29420674 Osteoinductive potential of 4 commonly employed bone grafts.
2. Herold RW, Pashley DH, Cuenin MF, et al. The effects of Varying degrees of Allograft Decalcification on Cultured Porcine Osteoclast cells. J Periodontol. 2002 Feb; 73(2):213–9
3. Mott DA, Mailhot J, Cuenin MF, et al. Enhancement of osteoblast proliferation in vitro by selective enrichment of demineralized freeze-dried bone allograft with specific growth factors. J Oral Implantol. 2002; 28(2):57–66
4. McLean JB, Carter N, Sohoni P, Moore MA. Cell attachment and osteoinductive properties of tissue engineered, demineralized bone fibers for bone void filling applications. Clinical Implementation of Bone Regeneration and Maintenance, IntechOpen. 2021.
5. Rodriguez RU, Kemper N, Breathwaite E, et al. Demineralized bone matrix fibers formable as general and custom 3D printed mold-based implants for promoting bone regeneration. Biofabrication. 2016;8(3):035007.
6. Boyan BD, Ranly DM, McMillan J, et al. Osteoinductive Ability of Human Allograft Formulations. J Periodontol. September 2006.
7. Dr. Byron Branch video, • Byron C. Branch, MD on PliaFX® Prime
8. Dr. Richard Yoon video, • Richard S. Yoon, MD on his use of PliaFX® ...